Amino acid metabolism lecture on Nonoxidative deamination.
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Deamination is the removal of an amine group from a molecule. Enzymes which catalyse this reaction are called deaminases. There are 4 types of deamination: intramolecular, resulting in the formation of unsaturated fatty acid; restorative, with formation of saturated fatty acid; hydrolytic, with formation of hydroxy carboxylic, and oxidative, with formation of a keto acid. In the human body, deamination takes place primarily in the liver, however glutamate is also deaminated in the kidneys. Deamination is the process by which amino acids are broken down if there is an excess of protein intake. The amino group is removed from the amino acid and converted to ammonia. The rest of the amino acid is made up of mostly carbon and hydrogen, and is recycled or oxidized for energy. Ammonia is toxic to the human system, and enzymes convert it to urea or uric acid by addition of carbon dioxide molecules (which is not considered a deamination process) in the urea cycle, which also takes place in the liver. Urea and uric acid can safely diffuse into the blood and then be excreted in urine. Source of the article published in description is Wikipedia. I am sharing their material. © by original content developers of Wikipedia.
Link- http://en.wikipedia.org/wiki/Main_Page
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Deamination is the removal of an amine group from a molecule. Enzymes which catalyse this reaction are called deaminases. There are 4 types of deamination: intramolecular, resulting in the formation of unsaturated fatty acid; restorative, with formation of saturated fatty acid; hydrolytic, with formation of hydroxy carboxylic, and oxidative, with formation of a keto acid. In the human body, deamination takes place primarily in the liver, however glutamate is also deaminated in the kidneys. Deamination is the process by which amino acids are broken down if there is an excess of protein intake. The amino group is removed from the amino acid and converted to ammonia. The rest of the amino acid is made up of mostly carbon and hydrogen, and is recycled or oxidized for energy. Ammonia is toxic to the human system, and enzymes convert it to urea or uric acid by addition of carbon dioxide molecules (which is not considered a deamination process) in the urea cycle, which also takes place in the liver. Urea and uric acid can safely diffuse into the blood and then be excreted in urine. Source of the article published in description is Wikipedia. I am sharing their material. © by original content developers of Wikipedia.
Link- http://en.wikipedia.org/wiki/Main_Page
Nonoxidative deamination biology major rutgers | |
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